Oct 5, 2023 · Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes
Oct 20, 2003
Phenytoin sodium is related to the barbiturates in chemical structure, but has a five-membered ring
e
IV phenytoin is different because the volume of the diluent plays a role in the chance of crystallization of IV phenytoin when mixed in normal saline
The drug is slowly administered
Initial dose (phenytoin-naive): 100 mg orally 3 times a day
For patients in the clinic or hospital
50 L/h/kg), inter-compartmental clearance (CLd = 1
The maximum single oral dose should not exceed 400 mg in order to minimize GI side effects and also increase absorption (decrease likelihood of concretions)
0
Common phenytoin side effects may include: drowsiness, confusion; slurred speech; abnormal eye movement; or
An increase to 600 mg/day may be needed
Phenytoin Sodium Injection, USP: 50 mg phenytoin sodium per milliliter is available as: 2 mL (100 mg) Single Dose vials
Correct: The rate of IV administration should not exceed 50 mg/min 3
Only use intravenous administration when these options are not feasible and where cardiac monitoring is available
015 mL in Water for Injection; hydrochloric acid added, if needed, for pH adjustment
Therapeutic effect without clinical signs of toxicity occurs more often with serum total concentrations between 10 and 20 mcg/mL (unbound phenytoin concentrations between 1 and 2 mcg/mL 11
IV phenytoin is different because the volume of the diluent plays a role in the chance of crystallization of IV phenytoin when mixed in normal saline
Control the rate of the drug by using the same rate of administration for the We would like to show you a description here but the site won’t allow us
Ensure continuous infusion of the drug
It is worth noting that, although the time taken to administer fosphenytoin (13 min, range 1–75 min) was significantly shorter than with phenytoin (45 min, range 15–165 min, P<0
The client with a seizure disorder is prescribed the anticonvulsant phenytoin (Dilantin)
Three (4
Phenytoin liquid 270mg once daily
Determination of phenytoin serum levels is advised when using Phenytoin Injection BP in the management of status epilepticus and in the subsequent establishing of maintenance dosage