64 μg/mL), BVDU is more than 100-folds
Like other virostatic drugs, it should be applied at least 5–6 times daily
Vidarabine therapy is reviewed briefly, and future new drugs with activity against herpesviruses are Seventy-three immunocompromised patients with disseminated herpes zoster were evaluated in a double-blind controlled trial of acyclovir (n = 37) versus vidarabine (n = 36) therapy
2, 8, 27, 28 Acyclovir replaced vidarabine in the treatment of HSV because of its superior efficacy and better safety profile
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About this article Vidarabine was the first antiviral agent used to treat HSV infections
[Google Scholar] [12] Sköldenberg B, Forsgren M
The present article is intended to provide a concise review of the available literature regarding the efficacy of antiviral drugs and other compounds with proven or Between 1980 and 2016, high-dose acyclovir treatment for neonatal HSV infection increased from 0% to close to 95%, with subsequent decrease in overall HSV-related mortality from 20
One hundred and twenty-seven patients with suspected herpes simplex encephalitis were entered in a randomised, controlled comparative study of therapy with acyclovir 10 mg/kg, 8-hourly, versus vidarabine, 15 mg/kg daily, for 10 days
An acyclovir or placebo bottle was ad-ministered at 8-h intervals for 7 days
5,6 We have compared the effect of acyclovir with that of vidarabine in HSE
We conducted a randomized trial to compare foscarnet with vidarabine in 14 patients with the acquired immunodeficiency syndrome (AIDS) and mucocutaneous herpetic lesions that
129 Acyclovir is most effective in severe VZV infection if administered intravenously (IV) within 24 hours after the rash develops
130 Oral acyclovir treatment of otherwise healthy children with chickenpox should be