It is primarily used as an antihypertensive and as an anti-anginal medication
The calcium channel blocker, nifedipine, can be administered safely in the setting of ventricular failure and appears to favorably alter resting and exercise hemodynamics
Nifedipine, a calcium channel blocker, inhibits inflammatory and fibrogenic gene expressions in advanced glycation end product (age)-exposed fibroblasts via
The recent study by Parmley et al 24 in patients with chronic stable angina showed that nifedipine-GITS reduced the weekly number of anginal episodes from 5
In this report, we will (a) discuss the mechanisms by which the calcium-channel antagonists, primarily nifedipine
Calcium channel blockers, including nifedipine, are widely used for the management of hypertension
The risk is greater in those with severe obstructive coronary artery disease
Data from over a ten-year period are presented
If you need surgery, tell the surgeon ahead of time that you are using nifedipine
Dose reduction may be needed in the second trimester when a 5-10 mm Hg decrease in mean blood pressure is often observed due to the physiologic changes of pregnancy
These problems may be less likely to occur if blood pressure is controlled
The benefit of such a long
The present study examined the effects of amlodipine or nifedipine treatment in a model of developing CHF on left ventricular (LV) pump function and myocyte contractility
There is a notable lack of high-quality evidence regarding the sickest patients
However, clinicians must be aware of
Kidneys receive about 20% of cardiac output which corresponds to about 1 L/minute
Calcium channel blockers may be used to treat heart failure caused by high blood pressure when other medications to lower blood pressure do not work
Glomerular filtration rate and effective renal plasma flow were increased 13
1990; 82:1954-1961
Possible loss of glycemic control