The rate increases at higher doses of amiodarone, particularly long-term use of doses over 500 mg daily
3 With the development of new therapeutic agents, catheter ablation, and implantable View This Abstract Online; Amiodarone: review of pulmonary effects and toxicity
Its primary effect
5 to 5 times normal), or clinical signs (possible hepatomegaly) during treatment for longer than
Though classified as a class III antiarrhythmic, it affects all phases of the
Paul Dieffenbach, MD Literature review current through: Dec 2023
After consultation with an infectious disease specialist and ruling out of other differential diagnoses as mentioned in , drug-induced fever and pulmonary toxicity from
Amiodarone
Introduction Amiodarone is a widely used medication used to treat various types of arrhythmias including atrial fibrillation
5
Phenytoin is a commonly prescribed anticonvulsant used to treat most types of seizure disorders and status epilepticus, with
ECMO for pulmonary rescue in an adult with amiodarone-induced toxicity
Anti-Arrhythmia Agents
Amiodarone therapy for heart dysrhythmia leads to lung toxicity in about 1-5% of cases
Some known adverse effects of amiodarone may be related to the dose and duration
Medscape UK - Indication-specific dosage for Amiodarone parenteral, precautions and warnings, side effects, pregnancy and lactation, contraindications and full drug monograph Administer as a dilute solution in 250ml 5% dextrose injection for a 150mg ampoule of amiodarone hydrochloride or 500ml 5% dextrose injection for a
Amiodarone is a class III antiarrhythmic drug used to treat atrial and ventricular arrhythmias
At 15-20 mcg/kg/min, acts on alpha-adrenergic receptors to increase systemic vascular resistance and raise BP
There are numerous side effects associated with amiodarone therapy including corneal deposits in over 90 percent of the patients taking the drug, abnormal liver function tests
5 mg/kg slow IV bolus over 2-3 minutes
dronedarone will increase the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism
USES: Sevelamer is used to lower high blood phosphorus (phosphate) levels in patients who are on dialysis due to severe kidney disease