The nodule might be the same color as the skin, or it might
Squamous cell carcinoma (SCC) accounts for most nonmelanoma skin cancer–related metastatic disease and deaths
Overview A type of skin cancer, which forms in the middle and outer layer of the skin
A flat sore with a scaly crust
The patient started a skin cancer suppression regimen of capecitabine 1000 mg twice a day, 7 days on, 7 days off, for a total of 6 months
Most are small, localized cancers
Standard therapy for patients with stage I-III squamous cell carcinoma (SCC) of the anal canal is chemo-radiotherapy with 5-fluorouracil (5-FU) and mitomycin C (MMC)
Cutaneous squamous cell carcinoma (cSCC), a malignant proliferation of cutaneous epithelium, represents 20% to 50% of skin cancers
Anal carcinoma (AC) Patients with a history of other malignancies (except resectable basal cell or squamous cell carcinoma of the skin), patients with recurrent disease at presentation and patients
Because some skin cancers demonstrate aggressive biologic behavior in the setting of immunosuppression, care must be taken to identify and treat early
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Because 5-FU and capecitabine have offered similar efficacy in many phase-III trials of solid tumours, studies have tested capecitabine in this setting of SCCAC
Non-melanoma skin cancers: background
Cutaneous squamous cell carcinoma (CSCC) is the second most common skin cancer after basal cell carcinoma, 1 with raising incidence worldwide over the decades
Cutaneous squamous cell carcinoma (cSCC) is the second most common nonmelanoma skin cancer, 1 accounting for 20% of all skin cancer deaths
J Cancer Res Clin Oncol