Note: A loading dose of 200-400 μg of levothyroxine may be given, with lower doses given for smaller or older patients and those with a history of coronary disease or
6 mcg/kg orally once a day
Capsule, Oral, as sodium: Tirosint: 13 mcg, 25 mcg, 50 mcg, 75 mcg, 88 mcg, 100 mcg, 112 mcg, 125 mcg, 137
6 mcg per kg of body weight
28 and 1
Current guidelines recommend a levothyroxine dosage of 1
Many people have a thyroid gland that cannot make
Titrate dosage every 6 to 8 weeks as needed until the patient is
It is a synthetic form of thyroxine, the main hormone produced by the thyroid gland
Indications to treat are women with symptomatic hypothyroidism and/or TSH values >10 mIU/L
Start at a lower starting dose in newborns (0-3 months) at risk for cardiac failure and Start levothyroxine sodium tablets at the full replacement dose in otherwise healthy, non-elderly individuals who have been hypothyroid for only a short time (such as a few months)
In this study, the authors evaluated the effect of sex, age and body weight on the blood level of thyroid hormone in patients taking Levothyroxine
Hashimoto’s thyroiditis often runs in families
Levothyroxine requirements frequently increase during pregnancy, usually by 25 to 50 percent
Current guidelines recommend that the dose of the thyroid hormone in hypothyroid patients should be adjusted to resolve symptoms and to keep the TSH level within a standard range
6 to 8 mcg/kg/day
When levothyroxine is taken in the correct dose, it has no side effects
5-25 mcg increments q4-6weeks until euthyroid
Thyroid hormone is generally taken in the Thyroid hormone Average dose is ~1
Table 1 Committee on Genetics ATA
8% in the second trimester and finally until delivery 84% of the cases need an increase in their levothyroxine dosage in comparison with preconception dosages (Table 2)
( PDF File for saving and printing, 407 KB) HYPOTHYROIDISM TSH reference ranges should be used to safely guide thyroid hormone treatment in hypothyroid patients
Pregnant patients: Levothyroxine should be dose titrated to achieve a TSH concentration within the following trimester-specific reference range: 0
Hypothyroidism is more common among elderly individuals due to the increasing incidence and prevalence of autoimmune thyroiditis that occurs with aging