Muscle damage with statins can be serious and may rarely cause kidney problems that could lead to death
However, the most common side effect is muscle pain and cramping
Mild symptoms include muscle pain, cramping, and perceived muscle weakness
Why do some people experience muscle pain with statins? Not everyone who takes a statin will have muscle pain
Take a lower dose Crestor (rosuvastatin) is a brand-name tablet prescribed to treat high cholesterol in adults and some children
Symptoms tend to start soon after you begin statin therapy
For many people, these side effects fade over time
Statin-induced myalgia is generally experienced as a soreness, usually in the shoulders and arms, or the hips and thighs
Your chances of getting muscle Muscle aches and pains Abdominal (stomach area) pain Weakness Nausea These side effects were reported to occur in at least 2% (at least 2 out of every 100 patients) in studies
The higher the dose of statins, the higher the risk of rhabdomyolysis becomes
In fact, around 12% of people taking Crestor has experienced muscle pain due to taking the drug
Serious Crestor side effects include high blood sugar and liver damage
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They cause muscle pain in under 5% of the people who take them, and these pains often stop by themselves even with continued statin use
Which statin is less likely to cause muscle pain? Atorvastatin, simvastatin, and fluvastatin are more likely to cause muscle aches as they are lipophilic, meaning they diffuse passively into the muscles
4% (3551 patients) developed symptoms of myalgia, a rate similar to that found in patients receiving a placebo
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Lescol, Pravachol, and Crestor appear to be less likely to cause health problems than other medications
It is also used to treat adults who cannot control their cholesterol levels by diet and exercise alone
A new study has shown that another drug called Nexletol (bempedoic acid) can help people lower their cholesterol and prevent heart disease without causing the muscle pain that can come with taking statins
As you correctly imply, statins are indeed associated with muscle pain and inflammation
Simvastatin is effective at lowering cholesterol; however, it may cause muscle pain particularly at higher dosages
Cholesterol could cause muscle pain, but there are no proven theories
Side effects include constipation, heartburn, nausea, diarrhea, and muscle pain
liver problems - upper stomach pain, tiredness, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes)
Most clinicians also acknowledge that statins are also linked to type 2 diabetes
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However, for more than 90% of patients on But, we do know that there are various levels of muscle symptoms associated with statins
They may also cause myopathies through an autoimmune effect, which means they trigger a body's attack Here's an overview of the pros and cons for common classes of cholesterol medications
Muscle pain, tenderness, or weakness - initially needs further Muscle pain
7%], myopathy and liver test Some options your provider may recommend to help with muscle pain while on a statin include: Lowering the dose of your medicine; Changing to a different statin—Lescol (fluvastatin) and Crestor (rosuvastatin) are less likely to cause muscle damage; Changing to a different class of drug, such as Zetia (ezetimibe) Check with your doctor immediately if any of the following side effects occur: Difficulty in moving
You may feel this pain as a soreness, tiredness or
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Stop taking rosuvastatin and call a doctor or call 111 now if: you get unexplained muscle pain, tenderness, weakness or cramps – these can be signs of muscle breakdown and
Difficulty in moving; joint pain or swelling;
Unregulated calcium leaks may cause damage to muscle cells, potentially leading to muscle pain and weakness
Other reported side effects of statins
Tips
Subjects were Elevated levels of CPK, or creatine kinase, a muscle enzyme that when elevated, can cause muscle pain, mild inflammation, and muscle weakness
Myalgia or muscle pain is the most common symptom and a frequent cause of statin discontinuation
Myalgia also often comes with mild feelings of weakness
inflammation of the liver (hepatitis), which can cause flu-like symptoms
However, in people already susceptible due to their genes or lifestyle, the leak caused by statins may overwhelm the muscle cells, giving rise to Cholesterol has been linked to muscle pain in the past, but no proven cause has been identified
Studies in women breastfeeding have demonstrated harmful infant effects
Research shows that muscle and joint aches occur in about 14% of people who take fluoroquinolone antibiotics
Since osteoarthritis and high cholesterol (and therefore statin use) are both very common, it is not surprising that muscle cramps, pain, spasms, stiffness, tenderness, wasting, or weakness
Increase in blood sugar (glucose) levels
(See "Statins: Actions, side effects, and administration"