4 Solubility
The outlet of the HPLC is coupled with an optical Lisinopril is used to treat high blood pressure, protect the kidneys in people with diabetes, and reduce the risk of death during a heart attack
The drug showed good solubility in water (90
Here we report a successful approach to solubility prediction in organic solvents and water using a combination of machine learning (ANN, SVM, RF
C=O is a moderately polar organic solvent while petroleum ether (a mixtures of alkanes) and hexanes are non-polar
In the organic laboratory, reactions are often run in nonpolar or slightly polar solvents such as toluene
US Patent 9,056,112 provided a process for preparation of linagliptin comprising reacting (R)-piperidine-3-amine or an acid addition salt thereof with 1-[(4
The study found that the modified Apelblat model and CNIBS/R-K model were the most appropriate for fitting the data