If the CAC score is 100 or greater or in the 75th percentile or greater, statin therapy is indicated Recommendations 1
2 of the NICE technology appraisal guidance on myocardial perfusion scintigraphy for the diagnosis and management of angina and myocardial infarction
[ NICE, 2013] Doctors are being advised to start prescribing statins to people with a lower risk threshold for cardiovascular disease following a review which has concluded the drugs could be suitable for a wider group of people
St John's Wort — plasma concentrations of calcium-channel blockers may be reduced by
The following are guideline recommendations for statin treatment: Patients ages 20-75 years and LDL-C ≥190 mg/dl, use high-intensity statin without risk assessment
Professor Jonathan Benger, NICE chief medical officer said: “Improving the control of cholesterol in a larger number of people will further reduce deaths from heart attacks and strokes
Due to age alone, patient B likely meets the risk threshold for statin initiation, but evidence of benefit and accurate CV risk estimation for someone his age is unclear
Authoring team
Looking at the clinical effectiveness of these drugs, in particular the high-intensity statins, the
In 2014, the National Institute for Health and Care Excellence (NICE) published its clinical guideline, ‘Cardiovascular disease: risk assessment and reduction, including lipid modification (CG181)’, which it subsequently updated in 2016