Target dose: 10 mg orally once a day; dose adjustments, if needed, should occur at intervals of not less than 1 week in 2
Use Caution/Monitor
For treatment of mania or mixed episodes with bipolar disorder (olanzapine alone): Adults—At first, 10 to 15 milligrams (mg) once a day
high fever excessive sweating rigid muscles confusion changes in breathing, heartbeat, or blood pressure DRESS warning: Olanzapine can cause a condition called
FDA has recently approved olanzapine in combination with samidorphan to attenuate olanzapine-induced weight gain
Published Aug
5 mg, injection) Medically reviewed by Drugs
Olanzapine is extensively metabolized to 10-N-glucuronide and 4-N-desmethyl-olanzapine by CYP450 1A2, 2D6 and glucuronidation, which are