Two case reports of cyclosporine toxicity attributable to interactions with the novel antidepressants nefazodone and fluvoxamine are presented
Trazodone is an antidepressant that works by inhibiting both serotonin transporter and serotonin type 2 receptors
Some products that may interact with this drug include: coal tar, orlistat, other drugs that weaken the immune system/increase the risk of infection (such as natalizumab
Trazodone is an antidepressant in the serotonin modulators class of
Cyclosporine: Strong P-gp inhibition and CYP3A4 inhibition 2: Combination is ok, monitor for bleeding 168: Minor: Itraconazole: Strong P-gp inhibition and moderate CYP3A4
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If a drug interaction involving CYP is likely, an alternate medication should be used
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Nine patients reported they had used tianeptine before, and six reported co-ingesting other substances, including alprazolam (a benzodiazepine), kratom (leaves
Trazodone tablets come as 50mg, 100mg and 150mg strengths
However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist
Check with your doctor immediately if any of the following side effects occur while taking trazodone: More common
Trazodone treats depressed mood and other depression-related symptoms and shows benefit in the treatment of insomnia due to its sedating effects
Other side effects not listed may also occur in some patients
Trazodone hydrochloride tablets should not be used within 14 days of an MAOI [see Warnings and Precautions (5
If you need it and do not get side effects, there's no reason to worry about taking trazodone for a long This drug can cause low sodium levels
Trazodone is a prescription drug used to treat depression and sleep disorders like insomnia
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Substantially increased plasma trazodone concentrations possible, with potential for adverse effects
Trazodone is only available as a generic drug; all brands have been discontinued
1 Pregnancy 8
Controlled 9
Of the total drug interactions, 154 are major, 580 are moderate, and 41 are minor
Side Effects
, < 150 mg/day), which
A person who has trouble sleeping Official answer
Other side effects, such as sexual One low-quality RCT showed more adverse effects, including morning grogginess, dry mouth, and thirst, at two weeks with trazodone (65
There are things you can do to help cope with them: Feeling sleepy or tired